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Patient In China Gets First Ever Gene-Altered Pig Liver Transplant

Researchers Are Trying To Find Ways To Make Organ Transplants Easier

In recent years, there has been an increase in the amount of space available for organ transplants, and researchers are trying to find ways to make these transplants easier. This latest development may help improve the quality of organ transplantation.

Chinese researchers have successfully transplanted a gene-engineered pig liver to a human transplant recipient for the first time in the world. The goal of this procedure is to help alleviate the shortage of organ donors. This development comes at a time when there is often an unending waiting list for organ donors.

Air Force Medical University performed the procedure on a brain-dead pig liver. The gene was transferred to the patient. In a recent post on WeChat, Air Force Medical University reported that the patient showed no evidence of organ rejection after 96 hours of surgery. The implications of this research are far-reaching. Liver disease causes over 2 million deaths each year. In China, where this research was conducted, it is estimated that 500,000 people face liver failure annually. This often leads to death due to the lack of organs available for transplantation. Even though liver transplants are life-saving, there are still few organ donors available. Xenotransplantation is a promising new approach to organ donation, especially when it comes to gene-editing pig organs.

Using genetically modified pigs, they can reduce the chance of organ rejection, and increase the supply of donor organs. This opens up a new way to treat liver diseases and save lives. However, the widespread use of transplantation raises some ethical and technical issues. Pig organs have great potential as replacements, but they are still very complicated in structure and function, limiting their ability to completely replace native organs. Therefore, researchers have developed innovative surgical techniques like auxiliary transplantation to improve compatibility and ensure that the organ functions optimally in the recipient’s body. The surgeons cut a large vein in the patient’s liver. After removing the donor pig from the patient, they trimmed the liver to a specific weight.


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